Examination of the Mode of Action of the Almiramide Family of Natural Products Against the Kinetoplastid Parasite Trypanosoma brucei

Almiramide C is a marine natural product with low micromolar activity against Leishmania donovani, the causative agent of leishmaniasis. We have now shown that almiramide C is also active against the related parasite Trypanosoma brucei, the causative agent of human African trypanosomiasis. A series...

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Main Authors: Sanchez, Laura M., Knudsen, Giselle M., Hartmann, Claudia, De Muylder, Geraldine, Mascuch, Samantha M., Mackey, Zachary B., Gerwick, Lena, Clayton, Christine, McKerrow, James H., Linington, Roger G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971013/
https://ncbi.nlm.nih.gov/pubmed/23445522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np300834q
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