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Differences in carrier frequency between mothers of Duchenne and Becker muscular dystrophy patients

Duchenne and Becker muscular dystrophies (DMD/BMD) are X-linked inherited muscular disorders caused by mutations in the dystrophin gene. Two-thirds of DMD cases are thought to be caused by inheritance from carrier mothers and this study aimed to clarify and compare the carrier frequency of mothers o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Tomoko, Takeshima, Yasuhiro, Kusunoki, Noriko, Awano, Hiroyuki, Yagi, Mariko, Matsuo, Masafumi, Iijima, Kazumoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970902/
https://ncbi.nlm.nih.gov/pubmed/24225992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2013.119
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