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Two novel missense mutations in the myostatin gene identified in Japanese patients with Duchenne muscular dystrophy
BACKGROUND: Myostatin is a negative regulator of skeletal muscle growth. Truncating mutations in the myostatin gene have been reported to result in gross muscle hypertrophy. Duchenne muscular dystrophy (DMD), the most common lethal muscle wasting disease, is a result of an absence of muscle dystroph...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855920/ https://ncbi.nlm.nih.gov/pubmed/17428346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-19 |
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