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Pentraxins and IgA share a binding hot-spot on FcαRI

The pentraxins, C-reactive protein (CRP), and serum amyloid P component (SAP) have previously been shown to function as innate opsonins through interactions with Fcγ receptors. The molecular details of these interactions were elucidated by the crystal structure of SAP in complex with FcγRIIA. More r...

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Detalhes bibliográficos
Main Authors: Lu, Jinghua, Marjon, Kristopher D, Mold, Carolyn, Marnell, Lorraine, Du Clos, Terry W, Sun, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-Blackwell 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970889/
https://ncbi.nlm.nih.gov/pubmed/24407959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2419
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