Recognition and functional activation of the human IgA receptor (FcαRI) by C-reactive protein

C-reactive protein (CRP) is an important biomarker for inflammatory diseases. However, its role in inflammation beyond complement-mediated pathogen clearance remains poorly defined. We identified the major IgA receptor, FcαRI, as a ligand for pentraxins. CRP recognized FcαRI both in solution and on...

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Bibliographic Details
Main Authors: Lu, Jinghua, Marjon, Kristopher D., Marnell, Lorraine L., Wang, Ruipeng, Mold, Carolyn, Du Clos, Terry W., Sun, Peter
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064353/
https://ncbi.nlm.nih.gov/pubmed/21383176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018369108
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