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Recognition and functional activation of the human IgA receptor (FcαRI) by C-reactive protein

C-reactive protein (CRP) is an important biomarker for inflammatory diseases. However, its role in inflammation beyond complement-mediated pathogen clearance remains poorly defined. We identified the major IgA receptor, FcαRI, as a ligand for pentraxins. CRP recognized FcαRI both in solution and on...

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Библиографические подробности
Главные авторы: Lu, Jinghua, Marjon, Kristopher D., Marnell, Lorraine L., Wang, Ruipeng, Mold, Carolyn, Du Clos, Terry W., Sun, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064353/
https://ncbi.nlm.nih.gov/pubmed/21383176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018369108
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