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Sequence variation and structural conservation allows development of novel function and immune evasion in parasite surface protein families

Trypanosoma and Plasmodium species are unicellular, eukaryotic pathogens that have evolved the capacity to survive and proliferate within a human host, causing sleeping sickness and malaria, respectively. They have very different survival strategies. African trypanosomes divide in blood and extracel...

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Autori principali: Higgins, Matthew K, Carrington, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley-Blackwell 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970887/
https://ncbi.nlm.nih.gov/pubmed/24442723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2428
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