Two separate functions of class II (Ia) molecules: T-cell stimulation and B-cell excitation.

We have evaluated the role of major histocompatibility complex-encoded class II (Ia) molecules as transmembrane signaling receptors in the T helper cell-dependent activation of B lymphocytes. For these studies, we utilized the murine B-cell lymphoma CH12, which expresses both I-A and I-E class II mo...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Corley, R B, LoCascio, N J, Ovnic, M, Haughton, G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3155862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.2.516
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