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Two separate functions of class II (Ia) molecules: T-cell stimulation and B-cell excitation.

We have evaluated the role of major histocompatibility complex-encoded class II (Ia) molecules as transmembrane signaling receptors in the T helper cell-dependent activation of B lymphocytes. For these studies, we utilized the murine B-cell lymphoma CH12, which expresses both I-A and I-E class II mo...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Corley, R B, LoCascio, N J, Ovnic, M, Haughton, G
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3155862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.2.516
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