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Infection in a rat model reactivates attenuated virulence after long-term axenic culture of Acanthamoeba spp

Prolonged culturing of many microorganisms leads to the loss of virulence and a reduction of their infective capacity. However, little is known about the changes in the pathogenic strains of Acanthamoeba after long culture periods. Our study evaluated the effect of prolonged culturing on the invasiv...

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Autors principals: Veríssimo, Carolina De Marco, Maschio, Vinícius José, Correa, Ana Paula Folmer, Brandelli, Adriano, Rott, Marilise Brittes
Format: Artigo
Idioma:Inglês
Publicat: Instituto Oswaldo Cruz 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970641/
https://ncbi.nlm.nih.gov/pubmed/24271042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-0276130099
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