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Latent luciferase activity in the fruit fly revealed by a synthetic luciferin

Beetle luciferases are thought to have evolved from fatty acyl-CoA synthetases present in all insects. Both classes of enzymes activate fatty acids with ATP to form acyl-adenylate intermediates, but only luciferases can activate and oxidize d-luciferin to emit light. Here we show that the Drosophila...

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Bibliographic Details
Main Authors: Mofford, David M., Reddy, Gadarla Randheer, Miller, Stephen C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970535/
https://ncbi.nlm.nih.gov/pubmed/24616520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319300111
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