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An Allosteric Modulator of Metabotropic Glutamate Receptors (mGluR(2)), (+)-TFMPIP, Inhibits Restraint Stress-Induced Phasic Glutamate Release in Rat Prefrontal Cortex

The potential anxiolytic effects of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor subgroup 2 (mGluR(2)) were investigated using a self-referencing recording technique with enzyme-based microelectrode arrays (MEAs) that reliably measures tonic and phasic changes i...

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Detalhes bibliográficos
Main Authors: Hascup, Erin R., Hascup, Kevin N., Pomerleau, Francois, Huettl, Peter, Hajos-Korcsok, Eva, Kehr, Jan, Gerhardt, Greg A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970435/
https://ncbi.nlm.nih.gov/pubmed/22578190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07784.x
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