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Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity.

Several ras genes have been expressed at high levels in Escherichia coli and the resultant ras proteins were shown to be functional with respect to their well-known specific, high-affinity, GDP/GTP binding. We were able to detect a weak GTPase activity associated with the purified proteins. The norm...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Manne, V, Bekesi, E, Kung, H F
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1985
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397041/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2982154/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.2.376
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