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Ca(2+)-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel

Phospholipid scramblases disrupt the lipid asymmetry of the plasma membrane, externalizing phosphatidylserine to trigger blood coagulation and mark apoptotic cells. Recently, members of the TMEM16 family of Ca(2+)-gated channels have been shown to be involved in Ca(2+)-dependent scrambling. It is ho...

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Detalles Bibliográficos
Main Authors: Malvezzi, Mattia, Chalat, Madhavan N., Janjusevic, Radmila, Picollo, Alessandra, Terashima, Hiroyuki, Menon, Anant K., Accardi, Alessio
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970400/
https://ncbi.nlm.nih.gov/pubmed/23996062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3367
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