Dense genomic sampling identifies highways of pneumococcal recombination

Evasion of clinical interventions by Streptococcus pneumoniae occurs through selection of non-susceptible genomic variants. Here we use genome sequencing of 3,085 pneumococcal carriage isolates from a 2.4 km(2) refugee camp to enable unprecedented resolution of the process of recombination, and high...

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Autori principali: Chewapreecha, Claire, Harris, Simon R, Croucher, Nicholas J, Turner, Claudia, Marttinen, Pekka, Cheng, Lu, Pessia, Alberto, Aanensen, David M, Mather, Alison E, Page, Andrew J, Salter, Susannah J., Harris, David, Nosten, Francois, Goldblatt, David, Corander, Jukka, Parkhill, Julian, Turner, Paul, Bentley, Stephen D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970364/
https://ncbi.nlm.nih.gov/pubmed/24509479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2895
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