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Pneumococcal Capsule Synthesis Locus cps as Evolutionary Hotspot with Potential to Generate Novel Serotypes by Recombination

Diversity of the polysaccharide capsule in Streptococcus pneumoniae—main surface antigen and the target of the currently used pneumococcal vaccines—constitutes a major obstacle in eliminating pneumococcal disease. Such diversity is genetically encoded by almost 100 variants of the capsule biosynthes...

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Dades bibliogràfiques
Publicat a:Mol Biol Evol
Autors principals: Mostowy, Rafał J., Croucher, Nicholas J., De Maio, Nicola, Chewapreecha, Claire, Salter, Susannah J., Turner, Paul, Aanensen, David M., Bentley, Stephen D., Didelot, Xavier, Fraser, Christophe
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850285/
https://ncbi.nlm.nih.gov/pubmed/28595308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx173
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