Single-Dose Intranasal Treatment with DEF201 (Adenovirus Vectored Consensus Interferon) Prevents Lethal Disease Due to Rift Valley Fever Virus Challenge

Rift Valley fever virus (RVFV) causes severe disease in humans and ungulates. The virus can be transmitted by mosquitoes, direct contact with infected tissues or fluids, or aerosol, making it a significant biological threat for which there is no approved vaccine or therapeutic. Herein we describe th...

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Bibliographic Details
Main Authors: Gowen, Brian B., Ennis, Jane, Bailey, Kevin W., Vest, Zachary, Scharton, Dionna, Sefing, Eric J., Turner, Jeffrey D.
Format: Artigo
Language:Inglês
Published: MDPI 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970158/
https://ncbi.nlm.nih.gov/pubmed/24662673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6031410
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