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Post-Exposure Vaccination with MP-12 Lacking NSs Protects Mice Against Lethal Rift Valley Fever Virus Challenge

Rift Valley fever virus (RVFV) causes severe disease in humans and livestock. There are currently no approved antivirals or vaccines for the treatment or prevention of RVF disease in humans. A major virulence factor of RVFV is the NSs protein, which inhibits host transcription including the interfer...

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Detalhes bibliográficos
Main Authors: Gowen, Brian B., Bailey, Kevin W., Scharton, Dionna, Vest, Zachery, Westover, Jonna B., Skirpstunas, Ramona, Ikegami, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665270/
https://ncbi.nlm.nih.gov/pubmed/23523764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.03.009
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