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Predictive combinatorial design of mRNA translation initiation regions for systematic optimization of gene expression levels
Balancing the amounts of enzymes is one of the important factors to achieve optimum performance of a designed metabolic pathway. However, the random mutagenesis approach is impractical since it requires searching an unnecessarily large number of variants and often results in searching a narrow range...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970122/ https://ncbi.nlm.nih.gov/pubmed/24682040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04515 |
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