Altered Macrophage Phenotype Transition Impairs Skeletal Muscle Regeneration

Monocyte/macrophage polarization in skeletal muscle regeneration is ill defined. We used CD11b-diphtheria toxin receptor transgenic mice to transiently deplete monocytes/macrophages at multiple stages before and after muscle injury induced by cardiotoxin. Fat accumulation within regenerated muscle w...

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Autors principals: Wang, Hanzhou, Melton, David W., Porter, Laurel, Sarwar, Zaheer U., McManus, Linda M., Shireman, Paula K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2014
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969996/
https://ncbi.nlm.nih.gov/pubmed/24525152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.020
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