Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

Altered lipid metabolism is increasingly recognized as a signature of cancer cells. Enabled by label-free Raman spectromicroscopy, we performed quantitative analysis of lipogenesis at single cell level in human patient cancerous tissues. Our imaging data revealed an unexpected, aberrant accumulation...

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Bibliografiset tiedot
Päätekijät: Yue, Shuhua, Li, Junjie, Lee, Seung-Young, Lee, Hyeon Jeong, Shao, Tian, Song, Bing, Cheng, Liang, Masterson, Timothy A., Liu, Xiaoqi, Ratliff, Timothy L., Cheng, Ji-Xin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969850/
https://ncbi.nlm.nih.gov/pubmed/24606897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.01.019
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