The let-7 MicroRNA Family Members mir-48, mir-84, and mir-241 Function Together to Regulate Developmental Timing in Caenorhabditis elegans

The microRNA let-7 is a critical regulator of developmental timing events at the larval-to-adult transition in C. elegans. Recently, microRNAs with sequence similarity to let-7 have been identified. We find that doubly mutant animals lacking the let-7 family micro-RNA genes mir-48 and mir-84 exhibit...

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Main Authors: Abbott, Allison L., Alvarez-Saavedra, Ezequiel, Miska, Eric A., Lau, Nelson C., Bartel, David P., Horvitz, H. Robert, Ambros, Victor
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969732/
https://ncbi.nlm.nih.gov/pubmed/16139228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2005.07.009
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