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A review of preclinical animal models utilised for TB vaccine evaluation in the context of recent human efficacy data()

There is an urgent need for an improved TB vaccine. Vaccine development is hindered by the lack of immune correlates and uncertain predictive value of preclinical animal models. As data become available from human efficacy trials, there is an opportunity to evaluate the predictive value of the crite...

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Autors principals: McShane, Helen, Williams, Ann
Format: Artigo
Idioma:Inglês
Publicat: Churchill Livingstone 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969587/
https://ncbi.nlm.nih.gov/pubmed/24369986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2013.11.003
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