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A review of preclinical animal models utilised for TB vaccine evaluation in the context of recent human efficacy data()

There is an urgent need for an improved TB vaccine. Vaccine development is hindered by the lack of immune correlates and uncertain predictive value of preclinical animal models. As data become available from human efficacy trials, there is an opportunity to evaluate the predictive value of the crite...

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Detalhes bibliográficos
Main Authors: McShane, Helen, Williams, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Churchill Livingstone 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969587/
https://ncbi.nlm.nih.gov/pubmed/24369986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2013.11.003
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