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A review of preclinical animal models utilised for TB vaccine evaluation in the context of recent human efficacy data()

There is an urgent need for an improved TB vaccine. Vaccine development is hindered by the lack of immune correlates and uncertain predictive value of preclinical animal models. As data become available from human efficacy trials, there is an opportunity to evaluate the predictive value of the crite...

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Detalles Bibliográficos
Autores principales: McShane, Helen, Williams, Ann
Formato: Artigo
Lenguaje:Inglês
Publicado: Churchill Livingstone 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969587/
https://ncbi.nlm.nih.gov/pubmed/24369986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2013.11.003
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