Tiotropium modulates transient receptor potential V1 (TRPV1) in airway sensory nerves: A beneficial off-target effect?(⋆)()

BACKGROUND: Recent studies have suggested that the long-acting muscarinic receptor antagonist tiotropium, a drug widely prescribed for its bronchodilator activity in patients with chronic obstructive pulmonary disease and asthma, improves symptoms and attenuates cough in preclinical and clinical tus...

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Main Authors: Birrell, Mark A., Bonvini, Sara J., Dubuis, Eric, Maher, Sarah A., Wortley, Michael A., Grace, Megan S., Raemdonck, Kristof, Adcock, John J., Belvisi, Maria G.
Format: Artigo
Jezik:Inglês
Izdano: Mosby 2014
Teme:
Asthma and Lower Airway Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969581/
https://ncbi.nlm.nih.gov/pubmed/24506933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.12.003
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