Mechanistic Insights into Self-Reinforcing Processes Driving Abnormal Histogenesis During the Development of Pancreatic Cancer

Pancreatic ductal adenocarcinoma, one of the most feared lethal and painful diseases, is increasing in incidence. The poor prognosis of pancreatic ductal adenocarcinoma–affected patients primarily is owing to our inability to develop effective therapies. Mechanistic studies of genetic, epigenetic, a...

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Главные авторы: Iovanna, Juan L., Marks, David L., Fernandez-Zapico, Martin E., Urrutia, Raul
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2013
Предметы:
Mini-Review
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969507/
https://ncbi.nlm.nih.gov/pubmed/23375449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.12.004
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