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Assessment of Active Pharmaceutical Ingredient Particle Size in Tablets by Raman Chemical Imaging Validated using Polystyrene Microsphere Size Standards

Particle size is a critical parameter for controlling pharmaceutical quality. The aim of this study was to assess the size of the micrometer-scale active pharmaceutical ingredients (API) in tablets using Raman chemical imaging and to understand the effects of formulation on particle size. Model tabl...

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Detalhes bibliográficos
Main Authors: Kuriyama, Atsushi, Ozaki, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969488/
https://ncbi.nlm.nih.gov/pubmed/24414886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-0064-9
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