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Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936()

Apolipoprotein E (APOE) ε genotype has previously been significantly associated with cognitive, brain imaging, and Alzheimer's disease-related phenotypes (e.g., age of onset). In the TOMM40 gene, the rs10524523 (“523”) variable length poly-T repeat polymorphism has more recently been associated...

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Bibliographische Detailangaben
Hauptverfasser: Lyall, Donald M., Harris, Sarah E., Bastin, Mark E., Muñoz Maniega, Susana, Murray, Catherine, Lutz, Michael W., Saunders, Ann M., Roses, Allen D., Valdés Hernández, Maria del C., Royle, Natalie A., Starr, John M., Porteous, David. J., Wardlaw, Joanna M., Deary, Ian J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969262/
https://ncbi.nlm.nih.gov/pubmed/24508314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.01.006
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