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Alzheimer’s Disease Susceptibility Genes APOE and TOMM40, and Hippocampal Volumes in the Lothian Birth Cohort 1936

The APOE ε and TOMM40 rs10524523 (‘523’) variable length poly-T repeat gene loci have been significantly and independently associated with Alzheimer’s disease (AD) related phenotypes such as age of clinical onset. Hippocampal atrophy has been significantly associated with memory impairment, a charac...

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Detalhes bibliográficos
Main Authors: Lyall, Donald M., Royle, Natalie A., Harris, Sarah E., Bastin, Mark E., Maniega, Susana Muñoz, Murray, Catherine, Lutz, Michael W., Saunders, Ann M., Roses, Allen D., del Valdés Hernández, Maria C., Starr, John M., Porteous, David. J., Wardlaw, Joanna M., Deary, Ian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829876/
https://ncbi.nlm.nih.gov/pubmed/24260406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080513
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