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Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis

Normal hemostasis requires von Willebrand factor (VWF) to support platelet adhesion and aggregation at sites of vascular injury. VWF is a multimeric glycoprotein built from identical subunits that contain binding sites for both platelet glycoprotein receptors and collagen. The adhesive activity of V...

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Detalhes bibliográficos
Main Authors: Stockschlaeder, Marcus, Schneppenheim, Reinhard, Budde, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams And Wilkins 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969155/
https://ncbi.nlm.nih.gov/pubmed/24448155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000065
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