Three-Component Coupling Approach for the Synthesis of Diverse Heterocycles Utilizing Reactive Nitrilium Trapping

[Image: see text] The formation of an unexpected heterocyclic scaffold, a benzoxazole, in a three-component reaction between a ketone, isocyanide, and 2-aminophenol was encountered. This reaction involved a benzo[b][1,4]oxazine intermediate resulting from intramolecular attack of the aminophenol hyd...

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Hlavní autoři: Váradi, András, Palmer, Travis C., Notis, Paula R., Redel-Traub, Gabriel N., Afonin, Daniel, Subrath, Joan J., Pasternak, Gavril W., Hu, Chunhua, Sharma, Indrajeet, Majumdar, Susruta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969103/
https://ncbi.nlm.nih.gov/pubmed/24580074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol500328t
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