Tat-Fused Recombinant Human SAG Prevents Dopaminergic Neurodegeneration in a MPTP-Induced Parkinson’s Disease Model

Excessive reactive oxygen species (ROS) generated from abnormal cellular process lead to various human diseases such as inflammation, ischemia, and Parkinson’s disease (PD). Sensitive to apoptosis gene (SAG), a RING-FINGER protein, has anti-apoptotic activity and anti-oxidant activity. In this study...

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Main Authors: Sohn, Eun Jeong, Shin, Min Jea, Kim, Dae Won, Ahn, Eun Hee, Jo, Hyo Sang, Kim, Duk-Soo, Cho, Sung-Woo, Han, Kyu Hyung, Park, Jinseu, Eum, Won Sik, Hwang, Hyun Sook, Choi, Soo Young
Format: Artigo
Language:Inglês
Published: Korean Society for Molecular and Cellular Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969043/
https://ncbi.nlm.nih.gov/pubmed/24625574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.2314
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