Tat-Fused Recombinant Human SAG Prevents Dopaminergic Neurodegeneration in a MPTP-Induced Parkinson’s Disease Model

Excessive reactive oxygen species (ROS) generated from abnormal cellular process lead to various human diseases such as inflammation, ischemia, and Parkinson’s disease (PD). Sensitive to apoptosis gene (SAG), a RING-FINGER protein, has anti-apoptotic activity and anti-oxidant activity. In this study...

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Autori principali: Sohn, Eun Jeong, Shin, Min Jea, Kim, Dae Won, Ahn, Eun Hee, Jo, Hyo Sang, Kim, Duk-Soo, Cho, Sung-Woo, Han, Kyu Hyung, Park, Jinseu, Eum, Won Sik, Hwang, Hyun Sook, Choi, Soo Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Molecular and Cellular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969043/
https://ncbi.nlm.nih.gov/pubmed/24625574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.2314
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