Association Analyses of Insulin Signaling Pathway Gene Polymorphisms With Healthy Aging and Longevity in Americans of Japanese Ancestry

Evidence from model organisms suggests that the insulin/IGF-1 signaling pathway has an important, evolutionarily conserved influence over rate of aging and thus longevity. In humans, the FOXO3 gene is the only widely replicated insulin/IGF-1 signaling pathway gene associated with longevity across mu...

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Bibliografische gegevens
Hoofdauteurs: Morris, Brian J., Donlon, Timothy A., He, Qimei, Grove, John S., Masaki, Kamal H., Elliott, Ayako, Willcox, D. Craig, Willcox, Bradley J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968832/
https://ncbi.nlm.nih.gov/pubmed/23770741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt082
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