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c-MYC-Induced Genomic Instability

MYC dysregulation initiates a dynamic process of genomic instability that is linked to tumor initiation. Early studies using MYC-carrying retroviruses showed that these viruses were potent transforming agents. Cell culture models followed that addressed the role of MYC in transformation. With the ad...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuzyk, Alexandra, Mai, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968784/
https://ncbi.nlm.nih.gov/pubmed/24692190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014373
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