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The RNA-binding protein Musashi-1 regulates proteasome subunit expression in breast cancer- and glioma-initiating cells

Cancer stem cells (CSCs) or tumor-initiating cells, similar to normal tissue stem cells, rely on developmental pathways, such as the Notch pathway, to maintain their stem cell state. One of the regulators of the Notch pathway is Musashi-1, a mRNA-binding protein. Musashi-1 promotes Notch signaling b...

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Autori principali: Lagadec, Chann, Vlashi, Erina, Frohnen, Patricia, Alhiyari, Yazeed, Chan, Mabel, Pajonk, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968686/
https://ncbi.nlm.nih.gov/pubmed/24022895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1537
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