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The RNA-binding protein Musashi-1 regulates proteasome subunit expression in breast cancer- and glioma-initiating cells

Cancer stem cells (CSCs) or tumor-initiating cells, similar to normal tissue stem cells, rely on developmental pathways, such as the Notch pathway, to maintain their stem cell state. One of the regulators of the Notch pathway is Musashi-1, a mRNA-binding protein. Musashi-1 promotes Notch signaling b...

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Detalhes bibliográficos
Main Authors: Lagadec, Chann, Vlashi, Erina, Frohnen, Patricia, Alhiyari, Yazeed, Chan, Mabel, Pajonk, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968686/
https://ncbi.nlm.nih.gov/pubmed/24022895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1537
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