Mutations in MAPT give rise to aneuploidy in animal models of tauopathy

Tau is a major microtubule-associated protein in brain neurons. Its misfolding and accumulation cause neurodegenerative diseases characterized by brain atrophy and dementia, named tauopathies. Genetic forms are caused by mutations of microtubule-associated protein tau gene (MAPT). Tau is expressed a...

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Hlavní autoři: Rossi, Giacomina, Conconi, Donatella, Panzeri, Elena, Paoletta, Laura, Piccoli, Elena, Ferretti, Maria Giulia, Mangieri, Michela, Ruggerone, Margherita, Dalprà, Leda, Tagliavini, Fabrizio
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968519/
https://ncbi.nlm.nih.gov/pubmed/24218087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-013-0380-y
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