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Mutations in MAPT give rise to aneuploidy in animal models of tauopathy
Tau is a major microtubule-associated protein in brain neurons. Its misfolding and accumulation cause neurodegenerative diseases characterized by brain atrophy and dementia, named tauopathies. Genetic forms are caused by mutations of microtubule-associated protein tau gene (MAPT). Tau is expressed a...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Berlin Heidelberg
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968519/ https://ncbi.nlm.nih.gov/pubmed/24218087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-013-0380-y |
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