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Feasibility of Repairing Glomerular Basement Membrane Defects in Alport Syndrome
Alport syndrome is a hereditary glomerular disease that leads to kidney failure. It is caused by mutations affecting one of three chains of the collagen α3α4α5(IV) heterotrimer, which forms the major collagen IV network of the glomerular basement membrane (GBM). In the absence of the α3α4α5(IV) netw...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Nephrology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968506/ https://ncbi.nlm.nih.gov/pubmed/24262794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013070798 |
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