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Tumor Lysing Genetically Engineered T Cells Loaded with Multi-Modal Imaging Agents
Genetically-modified T cells expressing chimeric antigen receptors (CAR) exert anti-tumor effect by identifying tumor-associated antigen (TAA), independent of major histocompatibility complex. For maximal efficacy and safety of adoptively transferred cells, imaging their biodistribution is critical....
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968458/ https://ncbi.nlm.nih.gov/pubmed/24675806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04502 |
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