Tumor Lysing Genetically Engineered T Cells Loaded with Multi-Modal Imaging Agents

Genetically-modified T cells expressing chimeric antigen receptors (CAR) exert anti-tumor effect by identifying tumor-associated antigen (TAA), independent of major histocompatibility complex. For maximal efficacy and safety of adoptively transferred cells, imaging their biodistribution is critical....

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Hlavní autoři: Bhatnagar, Parijat, Alauddin, Mian, Bankson, James A., Kirui, Dickson, Seifi, Payam, Huls, Helen, Lee, Dean A., Babakhani, Aydin, Ferrari, Mauro, Li, King C., Cooper, Laurence J. N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968458/
https://ncbi.nlm.nih.gov/pubmed/24675806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04502
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