The PNPLA3 Ile148Met interacts with overweight and dietary intakes on fasting triglyceride levels

The Ile148Met (rs738409, G-allele) in the patatin-like phospholipase domain-containing protein 3 gene (PNPLA3) associates with liver fat content and may lead to loss-of-function (hydrolysis) or gain-of-function (CoA-dependent lysophosphatidic acid acyltransferase) defects. PNPLA3 is up-regulated by...

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Autors principals: Stojkovic, Ivana A., Ericson, Ulrika, Rukh, Gull, Riddestråle, Martin, Romeo, Stefano, Orho-Melander, Marju
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968290/
https://ncbi.nlm.nih.gov/pubmed/24563329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-014-0388-4
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