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Fusion FISH Imaging: Single-Molecule Detection of Gene Fusion Transcripts In Situ

Double-stranded DNA breaks occur on a regular basis in the human genome as a consequence of genotoxic stress and errors during replication. Usually these breaks are rapidly and faithfully repaired, but occasionally different chromosomes, or different regions of the same chromosome, are fused to each...

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Bibliographic Details
Main Authors: Markey, Fatu Badiane, Ruezinsky, William, Tyagi, Sanjay, Batish, Mona
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968151/
https://ncbi.nlm.nih.gov/pubmed/24675777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093488
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