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Single-Molecule Imaging of Transcriptionally Coupled and Uncoupled Splicing

It is believed that the introns are removed from pre-mRNAs during transcription, while the pre-mRNA is still tethered to the gene locus via RNA polymerase. However, during alternative splicing it is important that splicing be deferred until all of the exons and introns involved in the choice have be...

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Detalhes bibliográficos
Main Authors: Vargas, Diana Y., Shah, Khyati, Batish, Mona, Levandoski, Michael, Sinha, Sourav, Marras, Salvatore A.E., Schedl, Paul, Tyagi, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245879/
https://ncbi.nlm.nih.gov/pubmed/22118462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.024
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