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Barriers to transmission of transcriptional noise in a c-fos c-jun pathway

We explored how transcriptional noise propagates in gene-regulatory pathways by studying the induction of two downstream genes by transcription factors c-fos and c-jun. They are produced for a brief period following serum stimulation of cells and then activate the promoters of their target genes by...

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Bibliographic Details
Main Authors: Shah, Khyati, Tyagi, Sanjay
Format: Artigo
Language:Inglês
Published: European Molecular Biology Organization 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792345/
https://ncbi.nlm.nih.gov/pubmed/24022005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2013.45
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