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Generation and Analysis of Novel Plant-Derived Antibody-Based Therapeutic Molecules against West Nile Virus
Previously, our group engineered a plant-derived monoclonal antibody (MAb) (pHu-E16) that efficiently treated West Nile virus (WNV) infection in mice. In this study, we developed several pHu-E16 variants to improve its efficacy. These variants included a single-chain variable fragment (scFv) of pHu-...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968140/ https://ncbi.nlm.nih.gov/pubmed/24675995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093541 |
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