Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus

Neutralization of West Nile virus (WNV) in vivo correlates with the development of an antibody response against the viral envelope (E) protein. Using random mutagenesis and yeast surface display, we defined individual contact residues of 14 newly generated monoclonal antibodies against domain III of...

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Detalhes bibliográficos
Main Authors: Oliphant, Theodore, Engle, Michael, Nybakken, Grant E, Doane, Chris, Johnson, Syd, Huang, Ling, Gorlatov, Sergey, Mehlhop, Erin, Marri, Anantha, Chung, Kyung Min, Ebel, Gregory D, Kramer, Laura D, Fremont, Daved H, Diamond, Michael S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458527/
https://ncbi.nlm.nih.gov/pubmed/15852016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1240
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