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Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus
Neutralization of West Nile virus (WNV) in vivo correlates with the development of an antibody response against the viral envelope (E) protein. Using random mutagenesis and yeast surface display, we defined individual contact residues of 14 newly generated monoclonal antibodies against domain III of...
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| Glavni autori: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group US
2005
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458527/ https://ncbi.nlm.nih.gov/pubmed/15852016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1240 |
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