Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus

Neutralization of West Nile virus (WNV) in vivo correlates with the development of an antibody response against the viral envelope (E) protein. Using random mutagenesis and yeast surface display, we defined individual contact residues of 14 newly generated monoclonal antibodies against domain III of...

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Bibliografische gegevens
Hoofdauteurs: Oliphant, Theodore, Engle, Michael, Nybakken, Grant E, Doane, Chris, Johnson, Syd, Huang, Ling, Gorlatov, Sergey, Mehlhop, Erin, Marri, Anantha, Chung, Kyung Min, Ebel, Gregory D, Kramer, Laura D, Fremont, Daved H, Diamond, Michael S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group US 2005
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458527/
https://ncbi.nlm.nih.gov/pubmed/15852016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1240
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