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Extracellular Proteolysis of Apolipoprotein E (apoE) by Secreted Serine Neuronal Protease
Under normal conditions, brain apolipoprotein E (apoE) is secreted and lipidated by astrocytes, then taken up by neurons via receptor mediated endocytosis. Free apoE is either degraded in intraneuronal lysosomal compartments or released. Here we identified a novel way by which apoE undergoes proteol...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968057/ https://ncbi.nlm.nih.gov/pubmed/24675880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093120 |
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