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Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics

EB1 is a conserved protein that plays a central role in regulating microtubule dynamics and organization. It binds directly to microtubule plus ends and recruits other plus end–localizing proteins. Most EB1-binding proteins contain a Ser–any residue–Ile-Pro (SxIP) motif. Here we describe the isolati...

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Detalhes bibliográficos
Main Authors: Leśniewska, Karolina, Warbrick, Emma, Ohkura, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967968/
https://ncbi.nlm.nih.gov/pubmed/24478452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-08-0504
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