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The rationale of vectored gene-fusion vaccines against cancer: evolving strategies and latest evidence
The development of vaccines that target tumor antigens in cancer has proven difficult. A major reason for this is that T cells specific for tumor self-antigens and neoantigens are eliminated or inactivated through mechanisms of tolerance. Antigen fusion strategies which increase the ability of vacci...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
SAGE Publications
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3967669/ https://ncbi.nlm.nih.gov/pubmed/24757514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2051013613480446 |
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