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The rationale of vectored gene-fusion vaccines against cancer: evolving strategies and latest evidence

The development of vaccines that target tumor antigens in cancer has proven difficult. A major reason for this is that T cells specific for tumor self-antigens and neoantigens are eliminated or inactivated through mechanisms of tolerance. Antigen fusion strategies which increase the ability of vacci...

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Detalhes bibliográficos
Main Authors: Ragonnaud, Emeline, Holst, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967669/
https://ncbi.nlm.nih.gov/pubmed/24757514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2051013613480446
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